Diet and insulin-dependent diabetes in the BB rat
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چکیده
منابع مشابه
Diet can prevent diabetes in the BB rat.
When compared with laboratory chow, a defined, semipurified diet prevented diabetes, reduced the frequency of insulitis, increased thymus weight and total white blood cell count, and doubled thymus T-helper/T-suppressor cell ratios in diabetes-prone BB rats. These data show that the diabetic syndrome in BB rats may be prevented or delayed by changes in diet, which may occur through alteration o...
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Introduction: Changes in saliva and its biochemical content in diabetic patients can effect on supportive dental tissues and cause dental damage. Low carbohydrate diets, and good control of disease can reduce dental damage in diabetics. The aim of this study was to compare dental damage in patients with non-insulin dependent diabetes mellitus (NIDDM) patients and healthy individuals. Methods: ...
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Objective: Serum Leptin concentration reflects the body fat mass. There is controversial reports about the insulin effect on serum Leptin concentration. We wanted to examine the effect of insulin therapy on serum Leptin in children with new onset type I diabetes. Materials and Methods: This was a Cross-Sectional study in Children's Medical Center on 34 children who had new onset type I diabe...
متن کاملEnteropathy precedes type 1 diabetes in the BB rat.
BACKGROUND AND AIMS There is increasing evidence implicating intestinal immune responses to dietary proteins in the pathogenesis of type 1 autoimmune diabetes (T1D). Here we investigated the association between intestinal pathology and dietary factors in T1D by examining the mucosal architecture in the BB rat model. METHODS BB control (BBc) and diabetes prone (BBdp) rats were fed either a dia...
متن کاملFK 506 prevents spontaneous diabetes in the BB rat.
The BB rat is the experimental analogue of human juvenile diabetes mellitus. From 30 through 120 days after birth, 59 BB rats were treated with water (n = 20), or FK 506 in daily intragastric doses of 1 mg/kg (n = 19) or 2 mg/kg (n = 20). Diabetes developed in 75%, 15%, and 0% of the three groups. Animals protected from diabetes by FK 506, and killed in the nondiabetic state at 120 days had nor...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1985
ISSN: 0012-186X,1432-0428
DOI: 10.1007/bf00277003